Factor I (1) or fibrinogen deficiency is an inherited bleeding disorder caused when a person’s body does not produce any or enough of a protein in the blood (fibrinogen) that plays an important role in blood clotting or the fibrinogen doesn’t work properly. It is very rare.
Links to selected resources:
Factor I (Fibrinogen) Deficiency
(World Federation of Hemophilia, 2023)
Explains the causes of Factor I deficiency, its symptoms, diagnosis and treatment.
Factor I deficiency (Fibrinogen deficiency)
(Canadian Hemophilia Society)
A comprehensive resource covering types of fibrinogen deficiency, causes, inheritance, symptoms, treatments, prevention, special precautions and specific problems for women.
Factor I deficiency
(National Hemophilia Foundation, USA)
Source: What are rare clotting factor deficiencies? World Federation of Hemophilia, Montreal, Canada, 2023.
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